Reservatrol for anti-cancer and longevity.
“Grapes are a prime source of reservatrol. Smaller but appreciable concentrations of the compound are found in red, white and rose wines, with the highest levels in red wine. Health benefits have previously been associated with moderate levels of wine consumption, particularly in terms of reduced risk of heart attack. Other natural sources high in reservatrol include mulberries and peanuts.
The researchers discovered reservatrol’s ability to inhibit cancer progression by treating human cancer cells (promyelocytic leukemia) with the compound. The diseased cells reverted to normal cells after treatment with reservatrol. In animal studies involving tumor-bearing mice, reservatrol proved effective against three major stages of cancer development: initiation (DNA in a cell is mutated), promotion (the affected cell becomes a cancer cell) and progression (cancer cells form a tumor and spread). Tests showed that reservatrol is an effective anti-inflammatory agent and inhibitor of cyclooxygenase, which plays a key role in tumor cell growth.
“What’s unusual is that anti-inflammatory agents often are solely anti-tumor promoters. Reservatrol has the added benefit of demonstrating anti-initiation and anti-progression activity,” Pezzuto said.”
“In grapes, resveratrol is found primarily in the skin and seeds. This is particularly true for muscadine grapes, whose skin and seeds have been reported to have about one hundred times the concentration as the pulp.”…Also “A Mississippi State University nutritionist reported that a purée of muscadine skins and pulp is an excellent source also of dietary fiber, essential minerals and carbohydrates and is low in fat. Muscadine purée powder has more dietary fiber than oat or rice bran.” (source)
I saw a 60 minutes episode last night that said that Reservatrol can help improve health and extend longevity in mice and there’s potential for humans. Sirtris Pharmaceuticals is still studying it. They’re also studying calorie restriction to prolong life. All that I advocate is you reading up on reservatrol and making a decision for yourself about it.
NY Times article: http://www.nytimes.com/2008/07/22/health/research/22long.html?_r=1&ref=research
More about Reservatrol:
Info/dose regarding Reservatrol:
Info about grape skins: http://www.answers.com/topic/grape-skin
High dose of reservatrol is in biotivia’s Transmax: http://www.biotivia.com/
Calorie restriction study: http://calerie.pbrc.edu/